THE 2-MINUTE RULE FOR SPORTS BETTING ONLINE

DNA ligases seal 5′-PO4 and three′-OH polynucleotide ends by way of 3 nucleotidyl transfer steps involving ligase-adenylate and DNA-adenylate intermediates. DNA ligases are crucial guardians of genomic integrity, and ligase dysfunction underlies human genetic condition syndromes. Crystal structures of DNA ligases bound to nucleotide and nucleic